An indole-based conductive biocompatible adhesive to promote charge transfer among nerve structures.
Abstract
Because of high clinical relevance and poor therapeutic strategies, restoration of electrical conduction between nerve structures or integrate neural bioelectronic interfaces will be explored using innovative biomaterials (Knoevenagel type indole derivatives with highly delocalized electrons, dispersed in biocompatible adhesives) to suitably recover the input conduction to physiological levels. This 24 month project will be carried out by six teams (at SISSA, UniUd and UniGe) combining chemical synthesis/formulation; electrochemical/mechanical characterization; and electrophysiological/behavioral, histological/ultrastructural, and biocompatibility analyses.
Partenariato
- Scuola Internazionale Superiore di Studi Avanzati di Trieste
- Università degli Studi di Genova
- Università degli Studi di Udine
Importo del progetto
Importo totale del progetto Euro 81.863,00
Importo del progetto Uniud Euro 56.781,00
Finanziamento Uniud Euro 25.082,00
Durata
- Dal 12/10/2023
- Al 11/10/2025
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