STIMOLA CURIOSITA’, PASSIONE E CORAGGIO
Identification of HERVs with prognostic and diagnostic value for preeclampsia
Abstract
Preeclampsia (PE) is a major cause of maternal and perinatal morbidity worldwide, leading to complications ranging from maternal stroke to fetal growth restriction and stillbirth. Two key events control hemochorial placentation: the fusion of cytotrophoblasts into syncytiotrophoblasts and the infiltration of the decidua and maternal endometrium and myometrium by extravillous trophoblasts Interestingly, syncytization is controlled by the de-repression of genes of retroviral origin (ERVs). Here we aim to identify the panel of HERVs with prognostic and diagnostic value for PE.
Partenariato
- Università di Cagliari
- Università degli studi di Udine
- Azienda sanitaria universitaria Friuli Centrale
Importo del progetto
Importo totale del progetto Euro 111.000,00
Importo del progetto Uniud Euro 111.000,00
Finanziamento Uniud Euro 0
Durata
- Dal 30/11/2023
- Al 29/11/2025
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