Docente

Dott. Loretta Franceschi loretta.franceschi@uniud.it

Crediti

6 CFU

Finalità

La finalità del corso è quella di fornire allo studente le conoscenze di farmacodinamica e farmacocinetica al fine di una corretta gestione dei farmaci.

Programma

• Farmacodinamica
• Farmacocinetica
• Forme farmaceutiche e modalità di somministrazione
• Chemioterapia antibatterica, antimicotica, antivirale, antiparassitaria
• Farmacologia endocrina

Esercitazioni

In aula verranno svolti esercizi di farmacocinetica rivolti in particolare al problema dei residui dei farmaci nelle derrate alimentari.

Bibliografia

Farmacologia generale e clinica per le lauree sanitarie – M. Furlanut – Ed. Piccin
Dispense fornite dal docente

Modalità di esame

Scritto

Objectives

The course provides the knowledge of the general concepts of pharmacokinetics and pharmacodynamics in relation to the use of drugs in animals, mode of preservation and administration, the variability of response to treatment pharmacological and non-pharmacological interactions, indications and contraindications. Particular attention will be paid to the problem of drug residues in foodstuffs.

Contents

Pharmacodynamic: drug-receptors interactions; agonist/antagonist and competitive/non competitive drugs; effects; pharmacodynamic interactions

Pharmacokinetic: aspects of absorption (passage through barriers); distribution; metabolism (induction and inhibition; first pass metabolism); and excretion ( urine, bile, espirated air, milk) drug). Determination of suspension time for free-drug food.

Interindividuality and intraspecies variability

Administration: storage and principal route of drug administration

Principal drug class: antibacterial, antivirus, antimycotic and antiparassitic chemotherapy; hormones

Pratical class

Pharmacokinetic exercises to evaluate principal pharmacokinetic parameters and in particular determination of suspension time for production of free-drug food