Proteoglycan-4 as coadjuvant treatment to overcome resistance to sorafenib and Regorafenib in patients with Hepatocellular carcinoma Proteoglycan-4 as coadjuvant treatment to overcome resistance to sorafenib and Regorafenib in patients with Hepatocellular carcinoma Proof Of Concept (POC) - PNRR M6/C2 2023